Description

Sodium Chloride 0.9% for Irrigation is a sterile, isotonic solution designed for specific medical applications. This clear, colourless solution is free from preservatives and is intended for external use only. It serves primarily as an irrigation solution during surgical procedures, effectively cleansing tissues, body cavities, wounds, indwelling urethral catheters, and surgical drainage tubes.

Composition

• Sodium Chloride: 0.9% concentration
• Excipients: Water for injection, hydrochloric acid, sodium hydroxide (for pH adjustment)
• pH Level: Approximately 5.75 (range 4.5–7.0)
• Osmolarity: 308 mOsmol/L

Physical Properties

• Electrolyte Content: Sodium 154 mEq/L, Chloride 154 mEq/L
• Molecular Formula: NaCl
• Molecular Weight: 58.44
• CAS Number: 7647-14-5

This solution is nonpyrogenic, with a relative density of approximately 1.00, making it miscible with water. It is non-flammable and non-combustible, ensuring safe handling.

Intended Use

Sodium Chloride 0.9% for Irrigation is not suitable for injection or intravenous use. It is a single-use solution, and any unused portion should be discarded after opening. It may also be used as a diluent for medications, such as inhalation solutions for nebulisation.

Administration

• Aseptic Technique: Essential during use
• Inspection: Ensure the solution is clear and the container is intact before use

Contraindications

• Not for use during electrosurgical procedures
• Not suitable for individuals with conditions like overhydration or pulmonary edema

Precautions

Care should be taken in patients with conditions such as congestive heart failure, renal impairment, or liver cirrhosis. Additives may be incompatible, and the solution should not be stored after mixing with additives.

Adverse Effects

Misuse may lead to fluid overload, electrolyte disturbances, or tissue disruption. Overdose symptoms can include gastrointestinal issues, metabolic acidosis, and hypernatremia.

Storage

• Temperature: Store below 25°C
• Protection: Keep away from light and freezing
• Warming: Do not exceed 66°C (150°F)
• Safety: Keep out of reach of children

Packaging

Available in single-use plastic ampoules or containers, with common sizes including 30 mL, 2000 mL, and 3000 mL. Pack sizes typically include 30 mL ampoules in packs of 30.

Safety and Handling

This product is not classified as hazardous and requires no special hazard labeling. Disposal should be conducted according to local regulations, avoiding release into drains.

Regulatory Status

Sodium Chloride 0.9% for Irrigation is unscheduled and not a controlled substance. All ingredients are listed on major international chemical inventories, ensuring compliance with regulatory standards.