Description

The 118-70MTG 7.0MM REINFORCED MURPH is an advanced surgical mesh device engineered to enhance surgical outcomes in procedures such as hernia repair and wound closure. This self-adhering, reinforced mesh provides exceptional mechanical support while promoting effective tissue adhesion, reducing the need for traditional sutures or staples.

Key Features

• Tissue Integration: The device supports rapid tissue ingrowth, acting as both a hemostatic agent and a barrier to post-surgical adhesions.
• Versatile Mesh Structure: Available in various shapes and sizes, the mesh may be synthetic, biological, degradable, or non-degradable, tailored to specific surgical needs.

Adhesive Matrix

The mesh is embedded within a cross-linkable protein matrix primarily composed of high-purity gelatin and microbial transglutaminase. This innovative adhesive matrix:

• Enhances Fixation: Activated by moisture or calcium solutions, providing strong initial fixation and minimizing mesh migration.
• Customizable Composition: Includes elements like calcium salts and alginate to facilitate cross-linking, with a carefully controlled enzyme-to-matrix ratio.

Backing Layer

A non-adhesive, water-erodable backing layer prevents unwanted adhesion during handling. Composed of polymers such as hydroxypropyl methylcellulose, it dissolves post-placement, leaving the crosslinked matrix to support tissue repair.

Multi-layer Structure

The device may feature multiple gelatin layers with varying densities, enhancing its adaptability. A bonding layer with polysaccharides or synthetic polymers improves tackiness and moisture control.

Sterilization and Manufacturing

• Sterilization: Achieved through electron beam radiation or ethylene oxide gas, ensuring a high sterility assurance level.
• Manufacturing Process: Involves foaming, casting, crosslinking, drying, and lyophilization, resulting in a device with optimal physical properties.

Supplementary Components

The device may include hemostatic agents, wound healing agents, antibiotics, and other bioactive substances to further enhance surgical outcomes. These components are tailored to specific needs, offering additional benefits such as radioprotection and lubrication.

Intended Applications

Designed for use in various surgical settings, the 118-70MTG 7.0MM REINFORCED MURPH excels in mesh fixation, tissue reinforcement, and sealing of wounds. Its design reduces the need for additional fixation methods, though it remains compatible with staples, tacks, and sutures if required.

Physical Properties

• Thickness: Typically ranges from 1.0 to 1.35 mm, with foam density carefully controlled.
• Size Variability: Available in diverse sizes and shapes to meet specific surgical demands.

Handling and Maintenance

The device's lyophilized form enhances shelf life and allows for rapid reconstitution. The dissolvable backing layer ensures ease of handling, preventing unwanted adhesion to gloves or tools.

This innovative medical implant is a valuable asset in surgical procedures, offering robust support, seamless integration, and tailored functionality to meet the complex demands of modern surgery.