Description

This premixed intravenous solution is designed for healthcare settings, providing essential electrolyte replenishment and fluid balance management. With a volume of 1000 mL, it contains Potassium Chloride at 30 mmol and Sodium Chloride at 0.9%, making it suitable for correcting and preventing hypokalaemia when oral supplementation is not feasible.

Key Features

• Clear and Colorless: The solution is preservative-free, ensuring purity and safety for intravenous use.
• Osmolarity and pH: With an osmolarity of 348 mOsm/L and a pH range of 4.5 to 7.0, it aligns well with physiological conditions.
• Packaging: Supplied in a single-use polyethylene bottle, it must be stored below 25°C and not frozen.

Administration

• Intravenous Use Only: Requires prescription in millimoles and should be administered using a rate-controlled infusion pump.
• Infusion Rates: For general wards, the recommended rate is 10 mmol/hour. Higher rates necessitate cardiac monitoring and are intended for critical care settings.
• Monitoring: Frequent monitoring of serum potassium and electrolytes is essential, with cardiac monitoring advised for higher infusion rates.

Safety Precautions

• High-Risk Medication: Should be stored separately to prevent dosing errors. Premixed solutions reduce the risk of accidental administration of concentrated potassium chloride.
• Contraindications: Includes conditions like hyperkalaemia, severe renal impairment, and congestive heart failure. Not intended for paediatric use without specific protocols.
• Compatibility: Not compatible with certain solutions like Mannitol 20% and Sodium Bicarbonate. Proper disposal of unused medicine is required.

Potential Adverse Effects

• Electrolyte Imbalances: May lead to hyperkalaemia, cardiac arrhythmias, and other cardiac-related issues.
• Local Reactions: Includes infection or inflammation at the injection site, thrombosis, and phlebitis.

Mechanism of Action

• Potassium and Sodium Balance: Potassium is crucial for nerve and muscle function, while Sodium maintains fluid balance. This solution supports these essential physiological roles, making it a vital component in clinical care under professional supervision.